Illustration of person with long hair on their phone

Digital depression therapy that puts your patient first

Using proven CBT techniques, deprexis® helps patients with depression make lasting progress.1,2

Help patients reclaim better days

deprexis® is one of the most researched digital therapies in the world, studied in 11 clinical trials with >2800 patients.1-11

Chatting icon

Making progress personal

Over the course of 10 content modules, deprexis® learns from patient input to provide responses that are customized to their specific needs.1

Therapist with patient icon

The CBT standard

deprexis® digitally integrates CBT techniques to alleviate negative thought and behavior patterns that block the potential for progress.1,12

Chart icon

Fits into any treatment plan

Whether a patient is new to therapy or seeking additional treatment, deprexis® fits in seamlessly.1

Clock icon

Always available

deprexis® is accessible 24/7 on desktop and mobile, giving patients access where and when they need it most.2,13

How it works image
Short Term

In a clinical study, people who added deprexis® to their care plan were 12x more likely to have an improvement in at least half of their symptoms compared with patients who did not add deprexis® to their care plan.2

Illustration of person thinking

Long Term

In another clinical study, patients who added deprexis® to their care plan saw a reduction in their depression symptoms 6 months after the program ended.1

Access to deprexis®

deprexis® is available to patients through their insurance provider, employer benefits, or through self-payment. Enroll in our deprexis® Compass program to find out if your patient is covered.

There when you need us

Our team is always here to answer any questions regarding access to deprexis®, coverage information, or technical support.

deprexis is a web application indicated for the adjunctive treatment of chronic or recurrent depression or depressive disorders as a primary or secondary diagnosis (eg, as a comorbidity in multiple sclerosis or epilepsy) for patients 18 years of age or older who are experiencing
a depressive episode.

References

1. Meyer B, Berger T, Caspar F, Beevers CG, Andersson G, Weiss M. Effectiveness of a novel integrative online treatment for depression (Deprexis): randomized controlled trial. J Med Internet Res. 2009;11(2):e15. doi:10.2196/jmir.1151. 2. Beevers CG, Pearson R, Hoffman JS, Foulser AA, Shumake J, Meyer B. Effectiveness of an internet intervention (deprexis) for depression in a United States adult sample: a parallel-group pragmatic randomized controlled trial. J Consult Clin Psychol. 2017;85(4):367-380. doi:10.1037/ccp0000171. 3. Meyer B, Bierbrodt J, Schröder J, et al. Effects of an internet intervention (deprexis) on severe depression symptoms: Randomized controlled trial. Internet Interventions. 2015;2(1):48-59. doi:10.1016/j.invent.2014.12.003. 4. Berger T, Hämmerli K, Gubser N, Andersson G, Caspar F. Internet-based treatment of depression: a randomized controlled trial comparing guided with unguided self-help. Cogn Behav Ther. 2011;40(4):251-266. doi:10.1080/16506073.2011.616531. 5. Moritz S, Schilling L, Hauschildt M, Schröder J, Treszl A. A randomized controlled trial of internet-based therapy in depression. Behav Res Ther. 2012;50(7-8):513-521. doi:10.1016/j.brat.2012.04.006. 6. Schröder J, Brückner K, Fischer A, et al. Efficacy of a psychological online intervention for depression in people with epilepsy: a randomized controlled trial. Epilepsia. 2014;55(12):2069-2076. doi:10.1111/epi.12833. 7. Fischer A, Schröder J, Vettorazzi E, et al. An online programme to reduce depression in patients with multiple sclerosis: a randomised controlled trial. Lancet Psychiatry. 2015;2(3):217-223. doi:10.1016/S2215-0366(14)00049-2. 8. Klein JP, Berger T, Schröder J, et al. Effects of a psychological internet intervention in the treatment of mild to moderate depressive symptoms: results of the EVIDENT study, a randomized controlled trial. Psychother Psychosom. 2016;85(4):218-228. doi:10.1159/000445355. 9. Berger T. Evaluating an e-mental health program ("deprexis") as adjunctive treatment tool in psychotherapy for depression: results of a pragmatic randomized controlled trial. J Affect Disord. 2017;227:455-462. 10. Zwerenz R, Becker J, Knickenberg RJ, et al. Online self-help as an add-on to inpatient psychotherapy: efficacy of a new blended treatment approach. Psychotherapy and Psychosomatics. 2017; 86(6):341-350. 11. Bücker L, Bierbrodt J, Hand I, Wittekind C, Moritz S. Effects of a depression-focused internet intervention in slot machine gamblers: a randomized controlled trial [published correction appears in PLoS One. Aug 23, 2018;13(8):e0203145]. PLoS One. 2018;13(6):e0198859. doi:10.1371/journal.pone.0198859. 12. American Psychological Association. What is cognitive behavioral therapy? Clinical practice guideline for the treatment of posttraumatic stress disorder. July 2017. Accessed June 9, 2020. https://www.apa.org/ptsd-guideline/patients-and-families/cognitive-behavioral.pdf. 13. Orexo acquires exclusive US rights to commercialize deprexis®, a world-leading digital therapy to help patients manage the symptoms of depression. News release. Orexo AB (publ.). May 11, 2020. Accessed October 30, 2020. https://orexo.com/media/regulatory-pressreleases?releaseId=9CC5F2D2BF210584.